[Q] - Best setup for NP using KODI??

I am setting up a media streaming device for someone who isn't tech savvy but wants to use NP for movies/tv/Netflix.. What are the best basic settings/config for using NP with Kodi and Netflix? They may or may not use external usb or mouse/keyboard.

5.1.1? Android M preview 3?
Rooted?
TWRP?
Custom Rom? CM12 / other??